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Spinal Muscular Atrophy Treatment Cost

The loss of muscle control, strength and movement are the few symptoms of Spinal Muscular Atrophy. It is a genetic disease which affects the central nervous system. The cost of SMA treatment in Hyderabad or spinal muscular atrophy treatment cost in Hyderabad generally depends on the type of SMA and the medicine taken. For example, the drug Zolgen also called onasemnogene abeparvovec, price in India crosses one crore.

What is Spinal Muscular Atrophy

The spinal cord consists of nerve cells, which control muscular function, and they get smaller (atrophy) as they are not stimulated by the nerve cells. This is how this disease is named SMA. It is a motor neuron disease causing the loss of nerve cells due to the lack of protein synthesis. They are divided into the following categories:

  • SMA -1: Also called Werdnig-Hoffman disease, which affects newborns under six months. Almost 60% of people with SMA suffer from Type-1 only. The SMA type 1 treatment cost in Hyderabad is expensive due to the high price of Onasemnogene abeparvovec in India, which is a drug used for treating SMA-1.

  • SMA-2: Best known as Dubowitz disease affects children between six months and 18 months old.

  • SMA-3:Alternatively, named as Kugelbert-Welander or Juvenile appears after 18 months in children.

  • SMA-4: This uncommon form of spinal muscular atrophy appears after the mid-30s.

Causes of Spinal Muscular Atrophy

This disease is a genetic abnormality. Generally, the patients lack either a portion of the SMN1 gene or carry an altered gene. The protein produced by the SMN1 gene helps motor neurons to function. These neurons gradually start dying in the SMA patient’s body. This results in losing the ability of voluntary movements, such as moving arms, legs, head or neck.

Treatment of SMA

The doctors do a thorough examination of the patient and check the family's medical history. The following tests are carried out:

  • Muscle Biopsy

  • Electromyography

  • Blood Tests

  • Amniocentesis or Chorionic Villus during pregnancy.

There is not a specific cure for SMA, it depends on the type and symptoms of the patient. However, physical and occupational therapy and assistive devices may help. These therapies also aid in the treatment:

  • Disease-modifying therapy

  • Gene Replacement Therapy

By now the U.S. FDA (Food and Drugs Administration) has approved three drugs for the medication of SMA: Nusinersen(Spinraza), Risdaplan (Evrysdi) and onasemnogene abeparvovec (Zolgensma).

Cost of Spinal Muscular Atrophy Treatment in Hyderabad is Extreme

As per the sources, the reason for high cost of SMA treatment in Hyderabad is due to the rare incidence of SMA. The additional value of the remarkable research in gene therapy for the development of the drugs and the tax on importing the drugs can be other reasons for the huge cost of Spinal Muscular Atrophy treatment in Hyderabad. With Spinraza, the SMA treatment price in Hyderabad may go up to INR 14,00,00,000, which has to be given to children under 2 years.

The spinal muscular atrophy injection cost in Hyderabad can be up to INR 16,00,000 as the onasemnogene abeparvovec price in India is around INR 16,00,000 with import tax. Since Zolgensma is given to kids for treating SMA-1, the treatment cost of SMA type 1 in Hyderabad is egregious.

Furthermore, Evrysdi price is around INR 6,00,000 per bottle, in India. This drug is given to adults, and children above 2 months for treating SMA, thus the charges for spinal muscular atrophy injection in Hyderabad are not very affordable.


FAQs

  1. Is there any alternative to reduce the cost of SMA type 1 treatment in Hyderabad? Unfortunately the cost for SMA injection treatment in Hyderabad or other parts of India only depends on the price of the drugs available. However, in many cases, people have received help from one place and another. You may also receive help from NGOs to collect the funds to aid in spinal muscular atrophy injection costs in Hyderabad.

  2. What are the symptoms of SMA?

    The symptoms depend on the type of SMA. But few common symptoms are

    • Progressive loss of muscles and reflexes

    • Inability to walk, sit, or stand

  3. Are there risks involved in the treatment of SMA?

    Yes, the medications have side effects since they involve genetic replacement and mutation.

  4. Can SMA be prevented?

    No, it can not be prevented. However, various therapies can assist the person to live a full and active life.

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