Department

Pancreatic Transplantation Centre

What is Pancreas Transplant?

Pancreatic transplantation is a surgical procedure in which a healthy donor pancreas, usually from a brain dead donor, is implanted into a patient whose pancreas fails. This is usually a type I diabetic patient (as well as highly selected type 2 diabetics) whose pancreas fails to produce the required insulin. This is a specialized procedure and is performed by a pancreatic transplant surgeon.

Once the pancreas is removed from the donor it is kept viable by cooling it and preserving in ice cold preservative solution. It can be preserved only for a few hours after it is removed from the donor. In addition, the donor’s blood type must be compatible with the patient receiving the organ so that the body has a better chance of accepting the organ.

During a pancreatic transplant, the native pancreas is not removed during the operation. This is because it is still capable of making the essential digestive enzymes needed during the digestion of food. Instead, the donor pancreas is placed below the diseased pancreas and is attached to the patient’s blood vessels.


What are the types of Pancreatic Transplants?

There are three types of pancreatic transplant options:

  • Combined Pancreas Kidney Transplant or Simultaneous Pancreas Kidney (SPK) Transplant: As stated earlier, sometimes a kidney transplant is required for those suffering from type I diabetes as well as renal failure. Often, the pancreas and kidney will come from the same donor and be transplanted at the same time.
  • Pancreas after Kidney (PAK) Transplant: .In this case, kidney transplantation is done first, either from a living donor or a deceased (cadaver) donor. Pancreas transplantation is done after some time in a kidney recipient with a functioning kidney graft.
  • Pancreas Transplant Alone (PTA): Pancreas transplants that do not require kidney transplants are for those who have severe type I diabetes (episodes of hypoglycemia. hypoglycemic unawareness, ketoacidosis) but are not having kidney failure. This procedure is also done in patients who undergo total pancreatectomy.

 

What are the advantages of a Pancreatic Transplants?

There is much to be gained from receiving a healthy pancreas, especially if you are suffering from extreme renal disease:

  • With a healthy pancreas, you may no longer require insulin injections that result from your type I diabetes.
  • Many of your type I diabetes symptoms may lessen or go away altogether with the presence of a healthy pancreas that is functioning as it was meant to.
  • A healthy pancreas will prevent further damage to your already unhealthy kidneys or work well with the new kidney you receive, should you require a kidney transplant as well. Other complications of severe diabetes (end organ damage) such as neuropathy (damage to the nervous system), retinopathy (damage to the eye), vasculopathy are improved or the progression arrested following successful pancreas transplantation.

 

What are the risks of a Pancreatic Transplants?

Here is a look at some of the possible risks and/or complications that may result from a pancreas transplant:

  • Your body may reject the new organ as a foreign object, attack it, and render it useless.
  • You will have to take immunosuppressant drugs for the rest of your life to help prevent your body from rejecting the new organ. These drugs can lower your immune system and trigger bacterial and viral infections, and increase the chances of some cancers. However, if you are, also, having renal transplant you would be taking immunosuppressant medications anyhow.
  • Since 75% of all pancreas transplants are performed with kidney transplants, complications post-surgery are higher with higher rates of rejection of the new organs.

What is Pancreas transplant?

A healthy donor pancreas is surgically inserted into a patient whose pancreas has failed in a surgery known as pancreatic transplantation. Typically, the donor is a brain dead individual. Typically, a type I diabetic patient (as well as a small percentage of type 2 diabetics) with inadequate pancreatic insulin production. A pancreas transplant surgeon performs this complex treatment. Once the pancreas has been extracted from the donor, it is preserved in an icy cold preservation solution to keep it alive. Only a few hours after being taken from the donor can it be kept. In order for the body to have a better chance of taking the organ, the blood types of the donor and recipient must match.The Best Pancreas Transplantation Hospital in Hyderabad varies from place to place. So before getting the treatment you must be aware of the Top Transplantation Hospital in Hyderabad and Pancreatitis Treatment Hospital In Hyderabad or you may visit KIMS hospital as KIMS hospital is the Best Pancreatitis Hospitals in Hyderabad.


The original pancreas is not taken out during a pancreatic transplant procedure. This is due to the fact that it can still produce the vital digestive enzymes required for food digestion. The donor pancreas is instead positioned beneath the sick pancreatic and fastened to the patient's blood arteries.

In Hyderabad the Pancreatitis Treatment Hospital In Hyderabad depends on a number of variables. To find out who the Best Pancreatitis in Hyderabad is, you must speak with the doctor.. But before knowing about the Best Pancreas Transplantation Hospital in Hyderabad, you must contact the doctors of KIMS hospital about the problem as KIMS hospital is the Pancreatitis Treatment Hospital In Hyderabad


What varieties of pancreatic transplants are there?

There are three different alternatives for pancreas transplants:

1. Simultaneous pancreas and kidney (SPK) transplant:

As previously mentioned, people with type I diabetes and renal failure may need a combined pancreas and kidney transplant, often known as a simultaneous pancreas and kidney (SPK) transplant. The kidney and pancreas are frequently transplanted at the same time from the same donor.

2. After Kidney (PAK) Transplant, Pancreas:

In this instance, a kidney transplant from either a living or a deceased (cadaver) donor is performed first. After some time has passed, a kidney recipient with a functional kidney graft undergoes pancreas transplantation. Top Transplantation Hospital in Hyderabad is KIMS Hospital it is worth getting treatment there

3. Pancreas Transplant Alone (PTA):

For those with severe type I diabetes (hypoglycemia episodes, hypoglycemic unawareness, ketoacidosis), but who do not have kidney failure, pancreas transplants are an option. Patients who get a total pancreatectomy also undergo this operation.


What benefits can a pancreatic transplant provide?

Receiving a healthy pancreas can be very beneficial, especially if you have severe renal disease:

1. You could no longer need the insulin injections that come with type I diabetes if your pancreas is in good health.

2. If your pancreas is healthy and working as it should, many of your type I diabetes symptoms may get better or go away entirely.


Procedures & Treatments

To choose the appropriate course of action, we individually consult with patients and their families:

1. TRANSPLANTS OF THE KIDNEY AND PANCREAS FOR PATIENTS: Simultaneous Pancreas and Kidney Transplant (SPK) and Pancreas after Kidney Transplant are the two varieties of combined kidney-pancreas transplant (PAK) In a simultaneous pancreas and kidney transplant (SPK), the dead donor's organs are used for both transplanted organs. Patients undergo both a pancreas and a kidney transplant during the same procedure. This treatment offers the best chance for many diabetics with renal failure to live a life free of dialysis or insulin shots. When the patient has a living kidney donor, the kidney transplant is carried out first using the living donor's kidney. This is known as pancreas after kidney transplant (PAK). After that, the patient awaits the availability of a deceased donor pancreas.

2. ONE-ON-ONE PANCREAS TRANSPLANT (PTA)

Patients with type 1 diabetes who have normal kidney function may be candidates for a pancreas-only transplant. A patient may want to consider pancreas transplantation when type 1 diabetes cannot be controlled (brittle diabetes) or is causing major issues (hypoglycemic unawareness or coma). Almost all recipients of a pancreas from a deceased donor no longer require insulin injections. After a transplant, their risk of kidney disease and other diabetic consequences may also be reduced.


FAQs


1. After a pancreatic transplant, what happens?

Results. After a successful pancreatic transplant, your new pancreas will produce the insulin your body requires, thus insulin therapy for type 1 diabetes won't be necessary anymore. But even if you and the donor are the finest possible match, your immune system will attempt to reject your new pancreas.


2. What conditions must be met before a pancreas transplant?

The majority of candidates for pancreatic transplant evaluation meet the following requirements: they must use insulin, have the necessary financial and social support for the pancreas transplant surgery and post-operative care, be under 55 years old, and be in good health.

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