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RISK FACTORS OF PARKINSONS DISEASE

Dr. S. Mohan Das, Friday, November 8, 2019

Risk Factors of Parkinson's Disease:

The damage in nerve cells with meager or no production of dopamine affectsthe function of the entire nervous system. This impairsa person’s ability to move and balance himself. This phenomenon is identified as Parkinson’s disease. The genuine reason is yet to be found out. But here are some of the factors that you cannot ignore.

Sex:

Males are more prone to get exposed to toxins or have a head trauma because of which Parkinson’s is found more in males than in females. It is theoretically proved that oestrogen has nuero-protective effects. Or the person carrying the X chromosome might become the victim of Parkinson’s when a gene is predisposed to him in case of a genetic predisposition.

Low in Oestrogen Levels:

People who have undergone hysterectomies and those who have not used an alternate remedy like hormonal replacement for post menopause are also a target of Parkinson’s disease.

Age:

As age advances there are a lot of changes that take place within the body. There are hardly or very few cases where the youngsters have been reported to have suffered from Parkinson’s. It’s very characteristic of Parkinson’s to grow slowly and worsen as one advances with age. The analysts believe that genetic and environmental factors also contribute to neural damage.

Vitamin B:

An experiment conducted by the researchers on the mice which had deficiency with Vitamin B developed symptoms of Parkinson’s while with the ones that had sufficient levels did not.

Family History:

When you notice the symptoms of Parkinson’s in one or more relatives you cannot deny that it is genetically linked as well. Yet, it cannot be concluded that as a greater factor to have Parkinson’s.

Genetic factors:

An international study led by Mayo clinic have concurred that a gene called alpha synuclein specially the active ones are more responsible for inducing Parkinson’s at some point of time in a man’s life. This has further led to development of anti alphasynuclein therapies to control or stop the disease in the long run.

Agricultural work:

People who are involved in farming as a profession or for livelihood or susceptible to this disease as they get exposed to herbicides and pesticides which affects the production of dopamine and damages nerve cells inducing Parkinson’s symptoms.

Head trauma:

A study in 2007 of around sixty patients have revealed a great source of truth that people with injuries in the head, neck or upper cervical spine have had severe cervical damage leading to Parkinson’s after few years or even sooner. The trauma has been the reason for its manifestation in the long run.

It’s very difficult to predict the onset of Parkinson’s with just these observations as factors as they may be the symptoms of various other diseases.It’s a rare disease that takes years to develop and when it does, it’s hard to clear the disease by itself other than controlling the symptoms or conduct surgeries that help him conduct his chores without being dependent on anyone.

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