Centre For Blood Disorders

Treatments & Procedures

The Hemophilia and Thrombosis Center at KIMS offers comprehensive evaluations and individualized care to children and adults with bleeding disorders due to hemophilia A, hemophilia B, rare clotting factor deficiencies and von Willebrand disease. We also evaluate and treat children with platelet-related bleeding disorders: ITP, thrombocytopenias due to other causes and disorders of platelet dysfunction. We have specialists in hematology, orthopedics and infectious diseases, in addition to hemophilia nursing and social services. We also provide comprehensive care to children, adolescents and adults with complex inherited or acquired thrombotic disorders, including deep venous thrombosis, pulmonary embolism and thrombotic thrombocytopenia purpura. For children without symptoms whose parents or other close relatives have suffered a major thrombotic event, we offer evaluations of and counselling for inherited risk factors.

The KIMS Sickle Cell Anemia Clinic is dedicated to prolonging and improving the lives of our patients with sickle cell disease. We offer medical treatment, psychological evaluation, education, counselling, referral to specialty services and team collaboration to determine the course of treatment best suited to your child. Treatment may include Hydroxyurea, a medication recently developed that may help reduce the frequency of pain crises and acute chest syndrome. It may also help decrease the need for frequent blood transfusions. We also prescribe lifelong antibiotic treatment for our patients with sickle cell disease to prevent risk of infection.

Von Willebrand disease (VWD) is an inherited disorder that affects the blood's ability to clot. People with VWD may experience heavy bleeding after an injury, leading to physical damage or even death. It is a cause of bleeding in early life and is often associated with family members who also have bleeding problems. But young children and adolescents without a family history of bleeding may suddenly have a bleeding problem. The disorder occurs as often in males as it does in females. Some children with a mild form of VWD do not need ongoing treatment; they may only need help after a medical procedure, including dental work, or after an accident that causes bleeding. Others may need to take medications. One common drug used to treat VWD is desmopressin, a hormone that causes the body to release more von Willebrand factor and factor VIII into the bloodstream. Another treatment is von Willebrand factor replacement therapy, which infuses von Willebrand factor and factor VIII into the body intravenously. Certain antifibrinolytic drugs—medicines that prevent blood clots from being destroyed—may also be prescribed. Aminocaproic acid and tranexamic are two examples of these drugs.If your child has a more serious form of VWD in which heavy bleeding is more likely, educate all caretakers, from teachers to sports coaches and the school nurse, about the disease and needed treatment in the event of an emergency.

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